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Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation
The Retinoblastoma (RB) tumor suppressor regulates G(1)/S transition during cell cycle progression by modulating the activity of E2F transcription factors. The RB pathway plays a central role in the suppression of most cancers, and RB mutation was initially discovered by virtue of its role in tumor...
Autores principales: | Kitajima, Shunsuke, Takahashi, Chiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581511/ https://www.ncbi.nlm.nih.gov/pubmed/28865172 http://dx.doi.org/10.1111/cas.13312 |
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