Inactivating mutations and hypermethylation of the NKX2‐1/TTF‐1 gene in non‐terminal respiratory unit‐type lung adenocarcinomas

The major driver mutations of lung cancer, EGFR mutations and EML4‐ALK fusion, are mainly detected in terminal respiratory unit (TRU)‐type lung adenocarcinomas, which typically show lepidic and/or papillary patterns, but are rarely associated with a solid or invasive mucinous morphology. In order to...

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Detalles Bibliográficos
Autores principales: Matsubara, Daisuke, Soda, Manabu, Yoshimoto, Taichiro, Amano, Yusuke, Sakuma, Yuji, Yamato, Azusa, Ueno, Toshihide, Kojima, Shinya, Shibano, Tomoki, Hosono, Yasuyuki, Kawazu, Masahito, Yamashita, Yoshihiro, Endo, Shunsuke, Hagiwara, Koichi, Fukayama, Masashi, Takahashi, Takashi, Mano, Hiroyuki, Niki, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581515/
https://www.ncbi.nlm.nih.gov/pubmed/28677170
http://dx.doi.org/10.1111/cas.13313

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