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Social Isolation in Early versus Late Adolescent Mice Is Associated with Persistent Behavioral Deficits That Can Be Improved by Neurosteroid-Based Treatment
Early trauma and stress exposure during a critical period of life may increase the risk of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) in adulthood. The first-choice treatment for MDD and PTSD are selective serotonin reuptake inhibitor (SSRI) antidepressants. Unfortunat...
Autores principales: | Locci, Andrea, Geoffroy, Philippe, Miesch, Michel, Mensah-Nyagan, Ayikoe-Guy, Pinna, Graziano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581875/ https://www.ncbi.nlm.nih.gov/pubmed/28900387 http://dx.doi.org/10.3389/fncel.2017.00208 |
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