HIPred: an integrative approach to predicting haploinsufficient genes

MOTIVATION: A major cause of autosomal dominant disease is haploinsufficiency, whereby a single copy of a gene is not sufficient to maintain the normal function of the gene. A large proportion of existing methods for predicting haploinsufficiency incorporate biological networks, e.g. protein-protein...

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Detalles Bibliográficos
Autores principales: Shihab, Hashem A, Rogers, Mark F, Campbell, Colin, Gaunt, Tom R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581952/
https://www.ncbi.nlm.nih.gov/pubmed/28137713
http://dx.doi.org/10.1093/bioinformatics/btx028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581952/
https://www.ncbi.nlm.nih.gov/pubmed/28137713
http://dx.doi.org/10.1093/bioinformatics/btx028

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