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Neonatal Diabetes and the K(ATP) Channel: From Mutation to Therapy
Activating mutations in one of the two subunits of the ATP-sensitive potassium (K(ATP)) channel cause neonatal diabetes (ND). This may be either transient or permanent and, in approximately 20% of patients, is associated with neurodevelopmental delay. In most patients, switching from insulin to oral...
Autores principales: | Ashcroft, Frances M., Puljung, Michael C., Vedovato, Natascia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Pub. Co
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582192/ https://www.ncbi.nlm.nih.gov/pubmed/28262438 http://dx.doi.org/10.1016/j.tem.2017.02.003 |
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