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Neonatal Diabetes and the K(ATP) Channel: From Mutation to Therapy

Activating mutations in one of the two subunits of the ATP-sensitive potassium (K(ATP)) channel cause neonatal diabetes (ND). This may be either transient or permanent and, in approximately 20% of patients, is associated with neurodevelopmental delay. In most patients, switching from insulin to oral...

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Detalles Bibliográficos
Autores principales: Ashcroft, Frances M., Puljung, Michael C., Vedovato, Natascia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Pub. Co 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582192/
https://www.ncbi.nlm.nih.gov/pubmed/28262438
http://dx.doi.org/10.1016/j.tem.2017.02.003

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