MYCN induces neuroblastoma in primary neural crest cells

Neuroblastoma (NBL) is an embryonal cancer of the sympathetic nervous system (SNS), which causes 15% of pediatric cancer deaths. High-risk NBL is characterized by N-Myc amplification and segmental chromosomal gains and losses. Owing to limited disease models, the etiology of NBL is largely unknown,...

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Detalles Bibliográficos
Autores principales: Olsen, R R, Otero, J H, García-López, J, Wallace, K, Finkelstein, D, Rehg, J E, Yin, Z, Wang, Y-D, Freeman, K W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582212/
https://www.ncbi.nlm.nih.gov/pubmed/28459463
http://dx.doi.org/10.1038/onc.2017.128

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