Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells

Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, fo...

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Detalles Bibliográficos
Autores principales: Niu, N, Mercado-Uribe, I, Liu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582213/
https://www.ncbi.nlm.nih.gov/pubmed/28436947
http://dx.doi.org/10.1038/onc.2017.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582213/
https://www.ncbi.nlm.nih.gov/pubmed/28436947
http://dx.doi.org/10.1038/onc.2017.72

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