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Dedifferentiation into blastomere-like cancer stem cells via formation of polyploid giant cancer cells
Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond. Intriguingly, fo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582213/ https://www.ncbi.nlm.nih.gov/pubmed/28436947 http://dx.doi.org/10.1038/onc.2017.72 |