A novel keratin 13 variant in a four‐generation family with white sponge nevus

We report a novel KRT13 germ line variant that causes white sponge nevus (WSN) with mucosal dysplasia. Genital, vaginal, and cervical WSN were observed in four female patients, of whom two had premalignant cervical lesions at young age. Two of the 12 patients with oral WSN developed oral squamous ce...

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Detalles Bibliográficos
Autores principales: de Haseth, Stephanie B., Bakker, Egbert, Vermeer, Maarten H., el Idrissi, Hakima, Bosse, Tjalling, Smit, Vincent T.H.B.M., Terron‐Kwiatkowski, Anna, McLean, W.H. Irwin, Peters, Alexander A.W., Hes, Frederik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582238/
https://www.ncbi.nlm.nih.gov/pubmed/28878914
http://dx.doi.org/10.1002/ccr3.1073
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author de Haseth, Stephanie B.
Bakker, Egbert
Vermeer, Maarten H.
el Idrissi, Hakima
Bosse, Tjalling
Smit, Vincent T.H.B.M.
Terron‐Kwiatkowski, Anna
McLean, W.H. Irwin
Peters, Alexander A.W.
Hes, Frederik J.
author_facet de Haseth, Stephanie B.
Bakker, Egbert
Vermeer, Maarten H.
el Idrissi, Hakima
Bosse, Tjalling
Smit, Vincent T.H.B.M.
Terron‐Kwiatkowski, Anna
McLean, W.H. Irwin
Peters, Alexander A.W.
Hes, Frederik J.
author_sort de Haseth, Stephanie B.
collection PubMed
description We report a novel KRT13 germ line variant that causes white sponge nevus (WSN) with mucosal dysplasia. Genital, vaginal, and cervical WSN were observed in four female patients, of whom two had premalignant cervical lesions at young age. Two of the 12 patients with oral WSN developed oral squamous cell carcinoma.
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spelling pubmed-55822382017-09-06 A novel keratin 13 variant in a four‐generation family with white sponge nevus de Haseth, Stephanie B. Bakker, Egbert Vermeer, Maarten H. el Idrissi, Hakima Bosse, Tjalling Smit, Vincent T.H.B.M. Terron‐Kwiatkowski, Anna McLean, W.H. Irwin Peters, Alexander A.W. Hes, Frederik J. Clin Case Rep Case Reports We report a novel KRT13 germ line variant that causes white sponge nevus (WSN) with mucosal dysplasia. Genital, vaginal, and cervical WSN were observed in four female patients, of whom two had premalignant cervical lesions at young age. Two of the 12 patients with oral WSN developed oral squamous cell carcinoma. John Wiley and Sons Inc. 2017-07-29 /pmc/articles/PMC5582238/ /pubmed/28878914 http://dx.doi.org/10.1002/ccr3.1073 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
de Haseth, Stephanie B.
Bakker, Egbert
Vermeer, Maarten H.
el Idrissi, Hakima
Bosse, Tjalling
Smit, Vincent T.H.B.M.
Terron‐Kwiatkowski, Anna
McLean, W.H. Irwin
Peters, Alexander A.W.
Hes, Frederik J.
A novel keratin 13 variant in a four‐generation family with white sponge nevus
title A novel keratin 13 variant in a four‐generation family with white sponge nevus
title_full A novel keratin 13 variant in a four‐generation family with white sponge nevus
title_fullStr A novel keratin 13 variant in a four‐generation family with white sponge nevus
title_full_unstemmed A novel keratin 13 variant in a four‐generation family with white sponge nevus
title_short A novel keratin 13 variant in a four‐generation family with white sponge nevus
title_sort novel keratin 13 variant in a four‐generation family with white sponge nevus
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582238/
https://www.ncbi.nlm.nih.gov/pubmed/28878914
http://dx.doi.org/10.1002/ccr3.1073
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