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Increased Hemodynamic Load in Early Embryonic Stages Alters Myofibril and Mitochondrial Organization in the Myocardium

Normal blood flow is essential for proper heart formation during embryonic development, as abnormal hemodynamic load (blood pressure and shear stress) results in cardiac defects seen in congenital heart disease (CHD). However, the detrimental remodeling processes that relate altered blood flow to ca...

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Detalles Bibliográficos
Autores principales: Midgett, Madeline, López, Claudia S., David, Larry, Maloyan, Alina, Rugonyi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582297/
https://www.ncbi.nlm.nih.gov/pubmed/28912723
http://dx.doi.org/10.3389/fphys.2017.00631

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