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Clinical development of CAR T cells—challenges and opportunities in translating innovative treatment concepts
Chimeric antigen receptor (CAR) T cell therapy, together with checkpoint inhibition, has been celebrated as a breakthrough technology due to the substantial benefit observed in clinical trials with patients suffering from relapsed or refractory B‐cell malignancies. In this review, we provide a compr...
Autores principales: | Hartmann, Jessica, Schüßler‐Lenz, Martina, Bondanza, Attilio, Buchholz, Christian J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582407/ https://www.ncbi.nlm.nih.gov/pubmed/28765140 http://dx.doi.org/10.15252/emmm.201607485 |
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