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Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle

Dengue virus (DENV) is transmitted to humans by Aedes mosquitoes and is a public health issue worldwide. No antiviral drugs specific for treating dengue infection are currently available. To identify novel DENV inhibitors, we analyzed a library of 95 compounds and 120 extracts derived from crude dru...

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Detalles Bibliográficos
Autores principales:	Hishiki, Takayuki, Kato, Fumihiro, Tajima, Shigeru, Toume, Kazufumi, Umezaki, Masahito, Takasaki, Tomohiko, Miura, Tomoyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582420/ https://www.ncbi.nlm.nih.gov/pubmed/28912773 http://dx.doi.org/10.3389/fmicb.2017.01674

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