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A tunable refractive index matching medium for live imaging cells, tissues and model organisms
In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate these mismatches, but they are so far limited to fixed samples. We present Iodixanol as a non-toxic mediu...
Autores principales: | Boothe, Tobias, Hilbert, Lennart, Heide, Michael, Berninger, Lea, Huttner, Wieland B, Zaburdaev, Vasily, Vastenhouw, Nadine L, Myers, Eugene W, Drechsel, David N, Rink, Jochen C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582871/ https://www.ncbi.nlm.nih.gov/pubmed/28708059 http://dx.doi.org/10.7554/eLife.27240 |
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