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Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD

The phosphatidylinositol 3-kinase (PI3K) pathway is activated in chronic obstructive pulmonary disease (COPD), but the regulatory mechanisms for this pathway are yet to be elucidated. The aim of this study was to determine the expression and role of phosphatase and tensin homolog deleted from chromo...

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Detalles Bibliográficos
Autores principales:	Yanagisawa, Satoru, Baker, Jonathan R., Vuppusetty, Chaitanya, Fenwick, Peter, Donnelly, Louise E., Ito, Kazuhiro, Barnes, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582930/ https://www.ncbi.nlm.nih.gov/pubmed/28522564 http://dx.doi.org/10.1152/ajplung.00382.2016

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