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Genetic and non-genetic determinants of thymic epithelial cell number and function

The thymus is the site of T cell development in vertebrates. In general, the output of T cells is determined by the number of thymic epithelial cells (TECs) and their relative thymopoietic activity. Here, we show that the thymopoietic activity of TECs differs dramatically between individual mouse st...

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Detalles Bibliográficos
Autores principales: Nagakubo, Daisuke, Krauth, Brigitte, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583284/
https://www.ncbi.nlm.nih.gov/pubmed/28871142
http://dx.doi.org/10.1038/s41598-017-10746-8

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