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Genetic and non-genetic determinants of thymic epithelial cell number and function
The thymus is the site of T cell development in vertebrates. In general, the output of T cells is determined by the number of thymic epithelial cells (TECs) and their relative thymopoietic activity. Here, we show that the thymopoietic activity of TECs differs dramatically between individual mouse st...
Autores principales: | Nagakubo, Daisuke, Krauth, Brigitte, Boehm, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583284/ https://www.ncbi.nlm.nih.gov/pubmed/28871142 http://dx.doi.org/10.1038/s41598-017-10746-8 |
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