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Functional prediction of long non-coding RNAs in ovarian cancer-associated fibroblasts indicate a potential role in metastasis

Cancer-associated fibroblasts (CAFs) contribute to the poor prognosis of ovarian cancer. Unlike in tumour cells, DNA mutations are rare in CAFs, raising the likelihood of other mechanisms that regulate gene expression such as long non-coding RNAs (lncRNAs). We aimed to identify lncRNAs that contribu...

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Detalles Bibliográficos
Autores principales: Vafaee, Fatemeh, Colvin, Emily K., Mok, Samuel C., Howell, Viive M., Samimi, Goli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583324/
https://www.ncbi.nlm.nih.gov/pubmed/28871211
http://dx.doi.org/10.1038/s41598-017-10869-y