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TRIB3 inhibits proliferation and promotes osteogenesis in hBMSCs by regulating the ERK1/2 signaling pathway
Osteogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBMSCs) is regulated by various factors, including bone morphogenetic proteins (BMPs), Notch, growth hormones and mitogen-activated protein kinases (MAPKs). Tribbles homolog 3 (TRIB3), a pseudokinase, plays an important...
Autores principales: | Zhang, Cui, Hong, Fan-Fan, Wang, Cui-Cui, Li, Liang, Chen, Jian-Ling, Liu, Fei, Quan, Ren-Fu, Wang, Jin-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583332/ https://www.ncbi.nlm.nih.gov/pubmed/28871113 http://dx.doi.org/10.1038/s41598-017-10601-w |
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