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Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment

An abnormal multicellular architecture is a defining characteristic of breast cancer and, yet, most in vitro tumor models fail to recapitulate this architecture or accurately predict in vivo cellular responses to therapeutics. The efficacy of two front-line chemotherapeutic agents (paclitaxel and ci...

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Detalles Bibliográficos
Autores principales:	Reynolds, Daniel S., Tevis, Kristie M., Blessing, William A., Colson, Yolonda L., Zaman, Muhammad H., Grinstaff, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583341/ https://www.ncbi.nlm.nih.gov/pubmed/28871147 http://dx.doi.org/10.1038/s41598-017-10863-4

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