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A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants

Conventional genetic screens for recessive mutants are inadequate for studying biological processes in the adult vertebrate due to embryonic lethality. Here, we report that a novel inducible mutagenesis system enables to study gene function in both embryonic and adult zebrafish. This system yields g...

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Detalles Bibliográficos
Autores principales: Ma, Zhipeng, Zhu, Peipei, Pang, Meijun, Guo, Liwei, Chang, Nannan, Zheng, Jiyuan, Zhu, Xiaojun, Gao, Ce, Huang, Honghui, Cui, Zongbin, Xiong, Jing-Wei, Peng, Jinrong, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583359/
https://www.ncbi.nlm.nih.gov/pubmed/28871129
http://dx.doi.org/10.1038/s41598-017-10968-w