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Fatty Acid Concentration and Phase Transitions Modulate Aβ Aggregation Pathways
Aggregation of amyloid β (Aβ) peptides is a significant event that underpins Alzheimer disease (AD) pathology. Aβ aggregates, especially the low-molecular weight oligomers, are the primary toxic agents in AD and hence, there is increasing interest in understanding their formation and behavior. Aggre...
Autores principales: | Rana, Pratip, Dean, Dexter N., Steen, Edward D., Vaidya, Ashwin, Rangachari, Vijayaraghavan, Ghosh, Preetam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583381/ https://www.ncbi.nlm.nih.gov/pubmed/28871093 http://dx.doi.org/10.1038/s41598-017-09794-x |
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