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Interleukin-17A is involved in mechanical hyperalgesia but not in the severity of murine antigen-induced arthritis

Interleukin-17A (IL-17A) is considered an important pro-inflammatory cytokine but its importance in joint diseases such as rheumatoid arthritis (RA) is unclear. It has also been reported that IL-17A may induce pain but it is unclear whether pro-inflammatory and pro-nociceptive effects are linked. He...

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Detalles Bibliográficos
Autores principales: Ebbinghaus, Matthias, Natura, Gabriel, Segond von Banchet, Gisela, Hensellek, Susanne, Böttcher, Martin, Hoffmann, Birgit, Salah, Firas Subhi, Gajda, Mieczyslaw, Kamradt, Thomas, Schaible, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583382/
https://www.ncbi.nlm.nih.gov/pubmed/28871176
http://dx.doi.org/10.1038/s41598-017-10509-5