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The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment
Given salvage treatment for recurrent nasopharyngeal carcinoma (NPC) remains a clinical dilemma, immunotherapy targeting NPC-specific immunosuppression may bring new hope. We analyzed the expression of CD8, CD4, Foxp3 and Tim-3 in lymphocytes, and of Galectin-9 in tumour cells between paired primary...
Autores principales: | Chen, Tseng-Cheng, Chen, Chao-Hsien, Wang, Cheng-Ping, Lin, Pei-Hsuan, Yang, Tsung-Lin, Lou, Pei-Jen, Ko, Jenq-Yuh, Wu, Chen-Tu, Chang, Yih-Leong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583393/ https://www.ncbi.nlm.nih.gov/pubmed/28871094 http://dx.doi.org/10.1038/s41598-017-10386-y |
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