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The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line

BACKGROUND/AIMS: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome. In this study, we elucidated whether NLRP3 -inf lamm...

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Detalles Bibliográficos
Autores principales: Uh, Soo-Taek, Koo, So My, Kim, Yangki, Kim, Kiup, Park, Sungwoo, Jang, An Soo, Kim, Dojin, Kim, Yong Hoon, Park, Choon-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583452/
https://www.ncbi.nlm.nih.gov/pubmed/28814068
http://dx.doi.org/10.3904/kjim.2016.033