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(-)-Epigallocatechin-3-gallate enhances poly I:C-induced interferon-λ1 production and inhibits hepatitis C virus replication in hepatocytes

AIM: To investigate the effect of (-)-epigallocatechin-3-gallate (EGCG) on polyinosinic-polycytidylic acid (poly I:C)-triggered intracellular innate immunity against hepatitis C virus (HCV) in hepatocytes. METHODS: A cell culture model of HCV infection was generated by infecting a hepatoma cell line...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Zhong, Li, Jie-Liang, Wang, Xu, Zhang, Ting, Ho, Wen-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583574/
https://www.ncbi.nlm.nih.gov/pubmed/28932081
http://dx.doi.org/10.3748/wjg.v23.i32.5895