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The development of T cells from stem cells in mice and humans

T cells develop from hematopoietic stem cells in the specialized microenvironment of the thymus. The main transcriptional players of T-cell differentiation such as Notch, Tcf-1, Gata3 and Bcl11b have been identified, but their role and regulation are not yet completely understood. In humans, functio...

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Detalles Bibliográficos
Autores principales:	Famili, Farbod, Wiekmeijer, Anna-Sophia, Staal, Frank JT
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583695/ https://www.ncbi.nlm.nih.gov/pubmed/28883990 http://dx.doi.org/10.4155/fsoa-2016-0095

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