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Control of cardiac ryanodine receptor by sarcoplasmic reticulum luminal Ca(2+)

Jones et al. propose that SR luminal Ca(2+) regulates RyR2 activity via a luminal Ca(2+) sensor distinct from the cytosolic Ca(2+) sensor.

Detalles Bibliográficos
Autores principales: Jones, Peter P., Guo, Wenting, Chen, S.R. Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583710/
https://www.ncbi.nlm.nih.gov/pubmed/28798281
http://dx.doi.org/10.1085/jgp.201711805
Descripción
Sumario:Jones et al. propose that SR luminal Ca(2+) regulates RyR2 activity via a luminal Ca(2+) sensor distinct from the cytosolic Ca(2+) sensor.