Abnormalities in the Polysomnographic, Adenosine and Metabolic Response to Sleep Deprivation in an Animal Model of Hyperammonemia

Patients with liver cirrhosis can develop hyperammonemia and hepatic encephalopathy (HE), accompanied by pronounced daytime sleepiness. Previous studies with healthy volunteers show that experimental increase in blood ammonium levels increases sleepiness and slows the waking electroencephalogram. As...

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Detalles Bibliográficos
Autores principales: Marini, Selena, Santangeli, Olena, Saarelainen, Pirjo, Middleton, Benita, Chowdhury, Namrata, Skene, Debra J., Costa, Rodolfo, Porkka-Heiskanen, Tarja, Montagnese, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583967/
https://www.ncbi.nlm.nih.gov/pubmed/28912724
http://dx.doi.org/10.3389/fphys.2017.00636

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