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Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
Polymorphisms in the T cell (or transmembrane) immunoglobulin and mucin domain 1 ( TIM-1) gene, particularly in the mucin domain, have been associated with atopy and allergic diseases in mice and human. Genetic- and antibody-mediated studies revealed that Tim-1 functions as a positive regulator of T...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584026/ https://www.ncbi.nlm.nih.gov/pubmed/30023044 http://dx.doi.org/10.12688/f1000research.8132.2 |