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Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies

Polymorphisms in the T cell (or transmembrane) immunoglobulin and mucin domain 1 ( TIM-1) gene, particularly in the mucin domain, have been associated with atopy and allergic diseases in mice and human. Genetic- and antibody-mediated studies revealed that Tim-1 functions as a positive regulator of T...

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Detalles Bibliográficos
Autores principales: Phong, Binh, Kane, Lawrence P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584026/
https://www.ncbi.nlm.nih.gov/pubmed/30023044
http://dx.doi.org/10.12688/f1000research.8132.2