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Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis
Myelopoiesis is necessary for the generation of mature myeloid cells during homeostatic turnover and immunological insults; however, the metabolic requirements for this process remain poorly defined. Here, we demonstrate that myelopoiesis, including monocyte and macrophage differentiation, requires...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584119/ https://www.ncbi.nlm.nih.gov/pubmed/28784627 http://dx.doi.org/10.1084/jem.20161855 |