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Structural differences between yeast and mammalian microtubules revealed by cryo-EM

Microtubules are polymers of αβ-tubulin heterodimers essential for all eukaryotes. Despite sequence conservation, there are significant structural differences between microtubules assembled in vitro from mammalian or budding yeast tubulin. Yeast MTs were not observed to undergo compaction at the int...

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Detalles Bibliográficos
Autores principales:	Howes, Stuart C., Geyer, Elisabeth A., LaFrance, Benjamin, Zhang, Rui, Kellogg, Elizabeth H., Westermann, Stefan, Rice, Luke M., Nogales, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584162/ https://www.ncbi.nlm.nih.gov/pubmed/28652389 http://dx.doi.org/10.1083/jcb.201612195

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