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Microtubule cross-linking activity of She1 ensures spindle stability for spindle positioning

Dynein mediates spindle positioning in budding yeast by pulling on astral microtubules (MTs) from the cell cortex. The MT-associated protein She1 regulates dynein activity along astral MTs and directs spindle movements toward the bud cell. In addition to localizing to astral MTs, She1 also targets t...

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Detalles Bibliográficos
Autores principales: Zhu, Yili, An, Xiaojing, Tomaszewski, Alexis, Hepler, Peter K., Lee, Wei-Lih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584168/
https://www.ncbi.nlm.nih.gov/pubmed/28794129
http://dx.doi.org/10.1083/jcb.201701094