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Dynamics of in vivo ASC speck formation

Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signaling platforms considered hallmarks of inflammasome activation. Because a lack of in vivo tools has prevented the study of endogenous ASC dynamics, we generated a live ASC reporter through C...

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Detalles Bibliográficos
Autores principales:	Kuri, Paola, Schieber, Nicole L., Thumberger, Thomas, Wittbrodt, Joachim, Schwab, Yannick, Leptin, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584180/ https://www.ncbi.nlm.nih.gov/pubmed/28701426 http://dx.doi.org/10.1083/jcb.201703103

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