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A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1

The nutrient starvation-specific unconventional secretion of Acb1 in Saccharomyces cerevisiae requires ESCRT-I, -II, and -III and Grh1. In this study, we report that another signal sequence lacking cytoplasmic protein, superoxide dismutase 1 (SOD1), and its mutant form linked to amyotrophic lateral...

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Detalles Bibliográficos
Autores principales:	Cruz-Garcia, David, Brouwers, Nathalie, Duran, Juan M., Mora, Gabriel, Curwin, Amy J., Malhotra, Vivek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584182/ https://www.ncbi.nlm.nih.gov/pubmed/28794127 http://dx.doi.org/10.1083/jcb.201704056

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