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Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility

Nonmuscle myosin II (NMII) is uniquely responsible for cell contractility and thus defines multiple aspects of cell behavior. To generate contraction, NMII molecules polymerize into bipolar minifilaments. Different NMII paralogs are often coexpressed in cells and can copolymerize, suggesting that th...

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Detalles Bibliográficos
Autores principales: Shutova, Maria S., Asokan, Sreeja B., Talwar, Shefali, Assoian, Richard K., Bear, James E., Svitkina, Tatyana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584186/
https://www.ncbi.nlm.nih.gov/pubmed/28701425
http://dx.doi.org/10.1083/jcb.201705167

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