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Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility
Nonmuscle myosin II (NMII) is uniquely responsible for cell contractility and thus defines multiple aspects of cell behavior. To generate contraction, NMII molecules polymerize into bipolar minifilaments. Different NMII paralogs are often coexpressed in cells and can copolymerize, suggesting that th...
Autores principales: | Shutova, Maria S., Asokan, Sreeja B., Talwar, Shefali, Assoian, Richard K., Bear, James E., Svitkina, Tatyana M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584186/ https://www.ncbi.nlm.nih.gov/pubmed/28701425 http://dx.doi.org/10.1083/jcb.201705167 |
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