Zebrafish earns its stripes for in vivo ASC speck dynamics

Assembly of the ASC speck is critical for signaling by the inflammasome. In this issue, Kuri et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703103) use live microscopy to track fluorescently tagged endogenous ASC in the zebrafish, describing the molecular domains driving ASC speck assemb...

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Detalles Bibliográficos
Autores principales: Bezbradica, Jelena S., Schroder, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584194/
https://www.ncbi.nlm.nih.gov/pubmed/28811279
http://dx.doi.org/10.1083/jcb.201708002
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author Bezbradica, Jelena S.
Schroder, Kate
author_facet Bezbradica, Jelena S.
Schroder, Kate
author_sort Bezbradica, Jelena S.
collection PubMed
description Assembly of the ASC speck is critical for signaling by the inflammasome. In this issue, Kuri et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703103) use live microscopy to track fluorescently tagged endogenous ASC in the zebrafish, describing the molecular domains driving ASC speck assembly and identifying a key role for macrophages in ASC speck removal in vivo.
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spelling pubmed-55841942018-03-04 Zebrafish earns its stripes for in vivo ASC speck dynamics Bezbradica, Jelena S. Schroder, Kate J Cell Biol Commentary Assembly of the ASC speck is critical for signaling by the inflammasome. In this issue, Kuri et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703103) use live microscopy to track fluorescently tagged endogenous ASC in the zebrafish, describing the molecular domains driving ASC speck assembly and identifying a key role for macrophages in ASC speck removal in vivo. The Rockefeller University Press 2017-09-04 /pmc/articles/PMC5584194/ /pubmed/28811279 http://dx.doi.org/10.1083/jcb.201708002 Text en © 2017 Bezbradica and Schroder http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Bezbradica, Jelena S.
Schroder, Kate
Zebrafish earns its stripes for in vivo ASC speck dynamics
title Zebrafish earns its stripes for in vivo ASC speck dynamics
title_full Zebrafish earns its stripes for in vivo ASC speck dynamics
title_fullStr Zebrafish earns its stripes for in vivo ASC speck dynamics
title_full_unstemmed Zebrafish earns its stripes for in vivo ASC speck dynamics
title_short Zebrafish earns its stripes for in vivo ASC speck dynamics
title_sort zebrafish earns its stripes for in vivo asc speck dynamics
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584194/
https://www.ncbi.nlm.nih.gov/pubmed/28811279
http://dx.doi.org/10.1083/jcb.201708002
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