How herpesviruses pass on their genomes

Herpesvirus genomes exist and replicate as episomes inside the host cell nucleus during latent infection. Chiu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201702013) find that unlike Epstein–Barr virus, which partitions viral genomes faithfully during cell division, Kaposi’s Sarcoma–asso...

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Detalles Bibliográficos
Autores principales: Serquiña, Anna K., Ziegelbauer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584196/
https://www.ncbi.nlm.nih.gov/pubmed/28819012
http://dx.doi.org/10.1083/jcb.201708077
Descripción
Sumario:Herpesvirus genomes exist and replicate as episomes inside the host cell nucleus during latent infection. Chiu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201702013) find that unlike Epstein–Barr virus, which partitions viral genomes faithfully during cell division, Kaposi’s Sarcoma–associated herpesvirus clusters viral genomes into loci that are distributed unequally to daughter cells.

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