Cargando…

Connexin40 controls endothelial activation by dampening NFκB activation

Connexins are proteins forming gap junction channels for intercellular communication. Connexin40 (Cx40) is highly expressed by endothelial cells (ECs) of healthy arteries but this expression is lost in ECs overlying atherosclerotic plaques. Low/oscillatory shear stress observed in bends and bifurcat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Denis, Jean-Francois, Scheckenbach, K.E. Ludwig, Pfenniger, Anna, Meens, Merlijn J., Krams, Rob, Miquerol, Lucile, Taffet, Steven, Chanson, Marc, Delmar, Mario, Kwak, Brenda R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584222/ https://www.ncbi.nlm.nih.gov/pubmed/28881621 http://dx.doi.org/10.18632/oncotarget.16438

Ejemplares similares

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release
por: Meens, Merlijn J, et al.
Publicado: (2015)

Connexin43 modulates neutrophil recruitment to the lung
por: Sarieddine, Maya Z Richani, et al.
Publicado: (2009)

Endothelial connexins in vascular function
por: Hautefort, Aurélie, et al.
Publicado: (2019)

CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts
por: Greenblatt, Matthew B., et al.
Publicado: (2015)

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress
por: Cacialli, Pietro, et al.
Publicado: (2021)

KLF4-Induced Connexin40 Expression Contributes to Arterial Endothelial Quiescence
por: Denis, Jean-François, et al.
Publicado: (2019)

Connexin40 regulates platelet function
por: Vaiyapuri, Sakthivel, et al.
Publicado: (2013)

Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo
por: Baeriswyl, Daniel C., et al.
Publicado: (2019)

Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity
por: Liu, Yuhao, et al.
Publicado: (2020)

Differential Association of Cx37 and Cx40 Genetic Variants in Atrial Fibrillation with and without Underlying Structural Heart Disease
por: Carballo, Sebastian, et al.
Publicado: (2018)

Lymphatic Connexins and Pannexins in Health and Disease
por: Ehrlich, Avigail, et al.
Publicado: (2021)

Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis
por: Molica, Filippo, et al.
Publicado: (2017)

Dampened STING-Dependent Interferon Activation in Bats
por: Xie, Jiazheng, et al.
Publicado: (2018)

Ex vivo, microelectrode analysis of conduction through the AV node of wild‐type and Nkx2‐5 mutant mouse hearts as guided by a Cx40‐eGFP transgenic reporter
por: Gazit, Avihu Z., et al.
Publicado: (2014)

Reduced tubuloglomerular feedback activity and absence of its synchronization in a connexin40 knockout rat
por: More, Heather L., et al.
Publicado: (2023)

CD40-Mediated Activation of the NF-κB2 Pathway
por: Hostager, Bruce S., et al.
Publicado: (2013)

Influence of V5/6-His Tag on the Properties of Gap Junction Channels Composed of Connexin43, Connexin40 or Connexin45
por: Desplantez, Thomas, et al.
Publicado: (2011)

Protein–Protein Interactions with Connexin 43: Regulation and Function
por: Sorgen, Paul L., et al.
Publicado: (2018)

Connexins and Pannexins in Vascular Function and Disease
por: Molica, Filippo, et al.
Publicado: (2018)

Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins
por: Badaoui, Mehdi, et al.
Publicado: (2023)

Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function
por: Molica, Filippo, et al.
Publicado: (2017)

Connexin43 mediates NF-κB signalling activation induced by high glucose in GMCs: involvement of c-Src
por: Xie, Xi, et al.
Publicado: (2013)

To dampen demyelination
por: Maxmen, Amy
Publicado: (2010)

Genetic variation at the human connexin 43 locus but not at the connexin 40 locus is associated with left bundle branch block
por: Ladenvall, Per, et al.
Publicado: (2015)

Connexin Communication Compartments and Wound Repair in Epithelial Tissue
por: Chanson, Marc, et al.
Publicado: (2018)

Early Steps of a Thymic Tumor in SV40 Transgenic Mice: Hyperplasia of Medullary Epithelial Cells and Increased Mature Thymocyte Numbers Disturb Thymic Export
por: Nabarra, Bernadette, et al.
Publicado: (2002)

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation
por: Zhou, Wenqing, et al.
Publicado: (2018)

Connexin26 Modulates the Radiosensitivity of Cutaneous Squamous Cell Carcinoma by Regulating the Activation of the MAPK/NF-κB Signaling Pathway
por: Sun, Minqiong, et al.
Publicado: (2021)

CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent
por: Kojok, Kevin, et al.
Publicado: (2018)

Advanced Glycation End Products Downregulate Connexin 43 and Connexin 40 in Diabetic Atrial Myocytes via the AMPK Pathway
por: Yang, Fan, et al.
Publicado: (2023)

Influence of Connexin40 on the renal myogenic response in murine afferent arterioles
por: Jacobsen, Jens Christian B, et al.
Publicado: (2015)

ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β
por: Robaszkiewicz, Agnieszka, et al.
Publicado: (2016)

Dampened neural activity and abolition of epileptic-like activity in cortical slices by active ingredients of spices
por: Pezzoli, Maurizio, et al.
Publicado: (2014)

Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network
por: Choquet, Caroline, et al.
Publicado: (2020)

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions
por: Di Meglio, Paola, et al.
Publicado: (2014)

Dampened regulates the activating potency of Bicoid and the embryonic patterning outcome in Drosophila
por: Liu, Junbo, et al.
Publicado: (2013)

C-type natriuretic peptide prevents angiotensin II-induced atrial connexin 40 and 43 dysregulation by activating AMP-activated kinase signaling
por: Ding, Da-Zhi, et al.
Publicado: (2019)

Aberrant CD40-Induced NF-κB Activation in Human Lupus B Lymphocytes
por: Zhang, Wen, et al.
Publicado: (2012)

PRAS40 promotes NF-κB transcriptional activity through association with p65
por: Zhu, G, et al.
Publicado: (2017)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
por: Rusiecka, Olga M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ua7vmsjppog8clskcoskful12t