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Preliminary biological evaluation of (18)F-AlF-NOTA-MAL-Cys-Annexin V as a novel apoptosis imaging agent
A novel annexin V derivative (Cys-Annexin V) with a single cysteine residue at its C-terminal has been successfully labeled site-specifically with NOTA-maleimide aluminum [(18)F]fluoride complexation and evaluated it as a novel apoptosis agent in vitro and in vivo. The total synthesis time of (18)F-...
Autores principales: | Lu, Chunxiong, Jiang, Quanfu, Hu, Minjin, Tan, Cheng, Yu, Huixin, Hua, Zichun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584233/ https://www.ncbi.nlm.nih.gov/pubmed/28881632 http://dx.doi.org/10.18632/oncotarget.16994 |
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