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Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry

Cruciferous vegetables such as broccoli and kale have well documented chemopreventative and anticancer effects that are attributed to the presence of isothiocyanates (ITCs). ITCs modulate the levels of many oncogenic proteins, but the molecular mechanisms of ITC action are not understood. We previou...

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Detalles Bibliográficos
Autores principales: Lawson, Ann P., Bak, Daniel W., Shannon, D. Alexander, Long, Marcus J.C., Vijaykumar, Tushara, Yu, Runhan, Oualid, Farid El, Weerapana, Eranthie, Hedstrom, Lizbeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584250/
https://www.ncbi.nlm.nih.gov/pubmed/28881649
http://dx.doi.org/10.18632/oncotarget.17261

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