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APEX2-enhanced electron microscopy distinguishes sigma-1 receptor localization in the nucleoplasmic reticulum

The sigma-1 receptor (Sig1R) is an endoplasmic reticulum chaperonin that is attracting tremendous interest as a potential anti-neurodegenerative target. While this membrane protein is known to reside in the inner nuclear envelope (NE) and influences transcription, apparent Sig1R presence in the nucl...

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Detalles Bibliográficos
Autores principales:	Mavlyutov, Timur A., Yang, Huan, Epstein, Miles L., Ruoho, Arnold E., Yang, Jay, Guo, Lian-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584251/ https://www.ncbi.nlm.nih.gov/pubmed/28881650 http://dx.doi.org/10.18632/oncotarget.17906

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