Activation of PERK branch of ER stress mediates homocysteine-induced BK(Ca) channel dysfunction in coronary artery via FoxO3a-dependent regulation of atrogin-1

The molecular mechanism of endoplasmic reticulum (ER) stress in vascular pathophysiology remains inadequately understood. We studied the role of ER stress in homocysteine-induced impairment of coronary dilator function, with uncovering the molecular basis of the effect of ER stress on smooth muscle...

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Detalles Bibliográficos
Autores principales: Sun, Wen-Tao, Wang, Xiang-Chong, Mak, Shiu-Kwong, He, Guo-Wei, Liu, Xiao-Cheng, Underwood, Malcolm John, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584261/
https://www.ncbi.nlm.nih.gov/pubmed/28881660
http://dx.doi.org/10.18632/oncotarget.17721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584261/
https://www.ncbi.nlm.nih.gov/pubmed/28881660
http://dx.doi.org/10.18632/oncotarget.17721

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