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miR-487b mitigates chronic heart failure through inhibition of the IL-33/ST2 signaling pathway

We investigated the effects of microRNA-587b (miR-487b) in a rat model of chronic heart failure (CHF). Wistar rats were assigned to 10 groups (n=8 per group). Expression of interleukin-33 (IL-33), somatostatin 2 (ST2), IL-6, and TNF-α was higher in the CHF group than the control group. In the CHF, n...

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Detalles Bibliográficos
Autores principales: Wang, En-Wei, Jia, Xu-Sheng, Ruan, Chang-Wu, Ge, Zhi-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584280/
https://www.ncbi.nlm.nih.gov/pubmed/28881679
http://dx.doi.org/10.18632/oncotarget.18393