Cargando…

Inhibition of COX2 enhances the chemosensitivity of dichloroacetate in cervical cancer cells

Dichloroacetate (DCA), a traditional mitochondria-targeting agent, has shown promising prospect as a sensitizer in fighting against malignancies including cervical cancer. But it is unclear about the effect of DCA alone on cervical tumor. Moreover, previous reports have demonstrated that the increas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Bo, Li, Xinzhe, Xiong, Haojun, Zhou, Peng, Ni, Zhenhong, Yang, Teng, Zhang, Yan, Zeng, Yijun, He, Jintao, Yang, Fan, Zhang, Nan, Wang, Yuting, Zheng, Yingru, He, Fengtian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584284/ https://www.ncbi.nlm.nih.gov/pubmed/28881683 http://dx.doi.org/10.18632/oncotarget.18518

Ejemplares similares

Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells
por: Li, Bo, et al.
Publicado: (2016)

Induction of SOCS3 by liver X receptor suppresses the proliferation of hepatocellular carcinoma cells
por: Xiong, Haojun, et al.
Publicado: (2017)

The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells
por: Wang, Bin, et al.
Publicado: (2014)

LncRNA LOC653786 promotes growth of RCC cells via upregulating FOXM1
por: Yang, Fan, et al.
Publicado: (2018)

Activation of Adenosine 2A receptor inhibits neutrophil apoptosis in an autophagy-dependent manner in mice with systemic inflammatory response syndrome
por: Liu, Yang-Wuyue, et al.
Publicado: (2016)

Dichloroacetate induces protective autophagy in esophageal squamous carcinoma cells
por: Jia, Hong-Yu, et al.
Publicado: (2017)

Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway
por: Liang, Yu, et al.
Publicado: (2019)

Superior anti-tumor efficacy of diisopropylamine dichloroacetate compared with dichloroacetate in a subcutaneous transplantation breast tumor model
por: Su, Lei, et al.
Publicado: (2016)

Clinical pharmacology and toxicology of dichloroacetate.
por: Stacpoole, P W, et al.
Publicado: (1998)

Anaerobic Microbial Metabolism of Dichloroacetate
por: Chen, Gao, et al.
Publicado: (2021)

Synergistic Antitumor Effect of Dichloroacetate in Combination with 5-Fluorouracil in Colorectal Cancer
por: Tong, Jingtao, et al.
Publicado: (2011)

Targeting Mitochondrial COX-2 Enhances Chemosensitivity via Drp1-Dependent Remodeling of Mitochondrial Dynamics in Hepatocellular Carcinoma
por: Che, Lin, et al.
Publicado: (2022)

A facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery
por: Yang, Conglian, et al.
Publicado: (2018)

Non-Hodgkin's Lymphoma Reversal with Dichloroacetate
por: Flavin, Dana F.
Publicado: (2010)

Repurposing dichloroacetate for the treatment of women with endometriosis
por: Horne, Andrew W., et al.
Publicado: (2019)

The expression of PLK-1 in cervical carcinoma: a possible target for enhancing chemosensitivity
por: Zhang, Yuan, et al.
Publicado: (2009)

The downregulation of ATG4B mediated by microRNA-34a/34c-5p suppresses rapamycin-induced autophagy
por: Wu, Yaran, et al.
Publicado: (2017)

Activation of FXR protects against renal fibrosis via suppressing Smad3 expression
por: Zhao, Kai, et al.
Publicado: (2016)

Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer
por: Zhou, Yang, et al.
Publicado: (2020)

Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells
por: de Mey, Sven, et al.
Publicado: (2020)

Synergistic Anti-tumor Effect of Dichloroacetate and Ivermectin
por: Ishiguro, Tatsuaki, et al.
Publicado: (2022)

Dichloroacetate inhibits the degeneration of decellularized cardiovascular implants
por: Chekhoeva, Agunda, et al.
Publicado: (2021)

Definitive extended field intensity-modulated radiotherapy and concurrent cisplatin chemosensitization in the treatment of IB2-IIIB cervical cancer
por: Zhang, Guangyu, et al.
Publicado: (2014)

Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
por: Duan, Yu, et al.
Publicado: (2013)

Novel ammonium dichloroacetates with enhanced herbicidal activity for weed control
por: Li, Huanhuan, et al.
Publicado: (2020)

Dichloroacetate ameliorates myocardial ischemia-reperfusion injury via regulating autophagy and glucose homeostasis
por: Li, Shuo, et al.
Publicado: (2019)

REV3L, a Promising Target in Regulating the Chemosensitivity of Cervical Cancer Cells
por: Yang, Li, et al.
Publicado: (2015)

Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice
por: Sun, Yanyan, et al.
Publicado: (2016)

In vitro cytotoxicity of combinations of dichloroacetate with anticancer platinum compounds
por: Olszewski, Ulrike, et al.
Publicado: (2010)

Dichloroacetate is an effective treatment for sarcoma models in vitro and in vivo
por: Rooke, Melissa, et al.
Publicado: (2014)

Dichloroacetate induces autophagy in colorectal cancer cells and tumours
por: Lin, G, et al.
Publicado: (2014)

Long-term stabilization of metastatic melanoma with sodium dichloroacetate
por: Khan, Akbar, et al.
Publicado: (2017)

Dichloroacetate (DCA) and Cancer: An Overview towards Clinical Applications
por: Tataranni, Tiziana, et al.
Publicado: (2019)

Dichloroacetate Stabilizes Mitochondrial Fusion Dynamics in Models of Neurodegeneration
por: O’Hara, Darren, et al.
Publicado: (2019)

Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
por: Mainali, Rabina, et al.
Publicado: (2021)

Chemoprevention with the metabolism modifying drugs dichloroacetate and metformin in Trp53+/- mice
por: Blackburn, AC, et al.
Publicado: (2012)

The effect of propofol on chemosensitivity of paclitaxel in cervical cancer cells
por: Jin, Yanshan, et al.
Publicado: (2023)

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
por: Michelakis, E D, et al.
Publicado: (2008)

Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
por: Sun, Ramon C, et al.
Publicado: (2011)

Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency
por: Rodrigues, Ana Sofia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ch8l4go3r7k2luv5cf5aasfncf