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Evaluating somatic tumor mutation detection without matched normal samples

BACKGROUND: Observations of recurrent somatic mutations in tumors have led to identification and definition of signaling and other pathways that are important for cancer progression and therapeutic targeting. As tumor cells contain both an individual’s inherited genetic variants and somatic mutation...

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Detalles Bibliográficos
Autores principales:	Teer, Jamie K., Zhang, Yonghong, Chen, Lu, Welsh, Eric A., Cress, W. Douglas, Eschrich, Steven A., Berglund, Anders E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584341/ https://www.ncbi.nlm.nih.gov/pubmed/28870239 http://dx.doi.org/10.1186/s40246-017-0118-2

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