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Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation
PURPOSE: Limbal epithelial stem cells (LSCs), located in the basal layer of the corneal epithelium in the corneal limbus, are vital for maintaining the corneal epithelium. LSCs have a high capacity of self-renewal with increased potential for error-free proliferation and poor differentiation. To dat...
Autores principales: | Gesteira, Tarsis F., Sun, Mingxia, Coulson-Thomas, Yvette M., Yamaguchi, Yu, Yeh, Lung-Kun, Hascall, Vincent, Coulson-Thomas, Vivien J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584473/ https://www.ncbi.nlm.nih.gov/pubmed/28863216 http://dx.doi.org/10.1167/iovs.17-22326 |
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