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Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma

Trauma is a major cause of systemic inflammatory response syndrome and multiple organ dysfunction syndrome. Macrophages (Mϕ) direct trauma-induced inflammation, and Mϕ death critically influences the progression of the inflammatory response. In the current study, we explored an important role of tra...

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Detalles Bibliográficos
Autores principales: Li, Zhigang, Fan, Erica K, Liu, Jinghua, Scott, Melanie J, Li, Yuehua, Li, Song, Xie, Wen, Billiar, Timothy R, Wilson, Mark A, Jiang, Yong, Wang, Ping, Fan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584526/
https://www.ncbi.nlm.nih.gov/pubmed/28492546
http://dx.doi.org/10.1038/cddis.2017.187