Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma

BACKGROUND: The overall response rate of hepatocellular carcinoma (HCC) to chemotherapy is poor. In our previous study, oxaliplatin-resistant HCC is found to exhibit an enhanced stemness, and increased levels of CCN2 and LRP6, while the role of CCN2 and LRP6 in the prognosis of HCC patients, and the...

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Detalles Bibliográficos
Autores principales: Jia, Qingan, Bu, Yang, Wang, Zhiming, Chen, Bendong, Zhang, Qiangbo, Yu, Songning, Liu, Qingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584530/
https://www.ncbi.nlm.nih.gov/pubmed/28870205
http://dx.doi.org/10.1186/s13046-017-0576-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584530/
https://www.ncbi.nlm.nih.gov/pubmed/28870205
http://dx.doi.org/10.1186/s13046-017-0576-3

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