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Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone
In previous studies we demonstrated that targeting the nuclear exporter protein exportin-1 (CRM1/XPO1) by a selective inhibitor of nuclear export (SINE) compound is a viable therapeutic strategy against Non-Hodgkin Lymphoma (NHL). Our studies along with pre-clinical work from others led to the evalu...
Autores principales: | Muqbil, Irfana, Aboukameel, Amro, Elloul, Sivan, Carlson, Robert, Senapedis, William, Baloglu, Erkan, Kauffman, Michael, Shacham, Sharon, Bhutani, Divaya, Zonder, Jeffrey, Azmi, Asfar S., Mohammad, Ramzi M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584550/ https://www.ncbi.nlm.nih.gov/pubmed/27693556 http://dx.doi.org/10.1016/j.canlet.2016.09.016 |
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