Cargando…

Monoacylglycerol O-acyltransferase 1 (MGAT1) localizes to the ER and lipid droplets promoting triacylglycerol synthesis

Monoacylglycerol acyltransferase 1 (MGAT) is a microsomal enzyme that catalyzes the synthesis of diacylglycerol (DAG) and triacylglycerol (TAG). However, the subcellular localization and catalytic function domain of this enzyme is poorly understood. In this report, we identified that murine MGAT1 lo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Yoo Jeong, Kim, Jae-woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584744/ https://www.ncbi.nlm.nih.gov/pubmed/28347400 http://dx.doi.org/10.5483/BMBRep.2017.50.7.036

Ejemplares similares

Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway
por: Petrie, James R., et al.
Publicado: (2012)

The monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells
por: McFie, Pamela J., et al.
Publicado: (2022)

Correction: Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway
por: Petrie, James R., et al.
Publicado: (2012)

Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis
por: Yu, Jung Hwan, et al.
Publicado: (2016)

Transmembrane Protein 68 Functions as an MGAT and DGAT Enzyme for Triacylglycerol Biosynthesis
por: Wang, Yu, et al.
Publicado: (2023)

Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans
por: Liss, Kim H. H., et al.
Publicado: (2018)

Hepatic Monoacylglycerol O-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes
por: Hayashi, Yasuhiro, et al.
Publicado: (2014)

Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei
por: Allmann, Stefan, et al.
Publicado: (2014)

Triacylglycerols sequester monotopic membrane proteins to lipid droplets
por: Caillon, Lucie, et al.
Publicado: (2020)

Applications of Diacylglycerol Acyltransferase for Triacylglycerol Production in Mortierella alpina
por: Yu, Ruilin, et al.
Publicado: (2023)

Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana
por: Divi, Uday K., et al.
Publicado: (2014)

N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase
por: Soni, Surabhi, et al.
Publicado: (2019)

Novel Insight into the Potential Role of Acylglycerophosphate Acyltransferases Family Members on Triacylglycerols Synthesis in Buffalo
por: Ma, Xiao-ya, et al.
Publicado: (2022)

Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells
por: Sankella, Shireesha, et al.
Publicado: (2016)

Retinyl esters form lipid droplets independently of triacylglycerol and seipin
por: Molenaar, Martijn R., et al.
Publicado: (2021)

Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1
por: Lutkewitte, Andrew J., et al.
Publicado: (2021)

Type 1 diacylglycerol acyltransferases of Brassica napus preferentially incorporate oleic acid into triacylglycerol
por: Aznar-Moreno, Jose, et al.
Publicado: (2015)

Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function
por: He, Yue, et al.
Publicado: (2014)

Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir
por: Wunderling, Klaus, et al.
Publicado: (2020)

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization
por: Take, Kazumi, et al.
Publicado: (2016)

Regular moderate aerobic exercise improves high-fat diet-induced nonalcoholic fatty liver disease via monoacylglycerol O-acyltransferase 1 pathway suppression
por: Baek, Kyung-Wan, et al.
Publicado: (2020)

Altered Lipid Droplet Dynamics in Hepatocytes Lacking Triacylglycerol Hydrolase Expression
por: Wang, Huajin, et al.
Publicado: (2010)

The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets
por: Khor, Victor K., et al.
Publicado: (2014)

Phospholipid: diacylglycerol acyltransferase contributes to the conversion of membrane lipids into triacylglycerol in Myrmecia incisa during the nitrogen starvation stress
por: Liu, Xiao-Yu, et al.
Publicado: (2016)

Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
por: Hall, Angela M., et al.
Publicado: (2014)

Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols
por: Dumesnil, Calvin, et al.
Publicado: (2023)

Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium
por: Lan, Chuanzeng, et al.
Publicado: (2021)

ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets
por: Du, Ximing, et al.
Publicado: (2019)

Expression of Mouse MGAT in Arabidopsis Results in Increased Lipid Accumulation in Seeds
por: El Tahchy, Anna, et al.
Publicado: (2015)

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface
por: Xu, Ningyi, et al.
Publicado: (2012)

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate
por: Li, Terytty Yang, et al.
Publicado: (2018)

Nannochloropsis, a rich source of diacylglycerol acyltransferases for engineering of triacylglycerol content in different hosts
por: Zienkiewicz, Krzysztof, et al.
Publicado: (2017)

Suppression of Cancer Progression by MGAT1 shRNA Knockdown
por: Beheshti Zavareh, Reza, et al.
Publicado: (2012)

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance
por: Cotte, Alexia Karen, et al.
Publicado: (2018)

Novel Cell-Based Assay to Investigate Monoacylglycerol Acyltransferase 2 Inhibitory Activity Using HIEC-6 Cell Line
por: Singh, Yeshvanthi, et al.
Publicado: (2021)

Getting a handle on lipid droplets: Insights into ER–lipid droplet tethering
por: Nguyen, Truc B., et al.
Publicado: (2019)

Characterization of a Haematococcus pluvialis Diacylglycerol Acyltransferase 1 and Its Potential in Unsaturated Fatty Acid-Rich Triacylglycerol Production
por: Cui, Hongli, et al.
Publicado: (2021)

Overexpression of DGAT2 Stimulates Lipid Droplet Formation and Triacylglycerol Accumulation in Bovine Satellite Cells
por: Zhang, Jun-Fang, et al.
Publicado: (2022)

Increased triacylglycerol production in oleaginous microalga Neochloris oleoabundans by overexpression of plastidial lysophosphatidic acid acyltransferase
por: Chungjatupornchai, Wipa, et al.
Publicado: (2019)

Transgenic Rescue of Spermatogenesis in Males With Mgat1 Deleted in Germ Cells
por: Biswas, Barnali, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e1ofbbep6je5cc8sgmv9qahh5k