Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein

The mycobacterial mel2 locus (mycobacterial enhanced infection locus, Rv1936-1941) is Mycobacterium marinum and M. tuberculosis specific, which can withstand reactive oxygen species (ROS) and reactive nitrogen species (RNS) induced stress. A library of over a million compounds was screened using in...

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Detalles Bibliográficos
Autores principales: Dharra, Renu, Talwar, Sakshi, Singh, Yogesh, Gupta, Rani, Cirillo, Jeffrey D., Pandey, Amit K., Kulharia, Mahesh, Mehta, Promod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584760/
https://www.ncbi.nlm.nih.gov/pubmed/28873466
http://dx.doi.org/10.1371/journal.pone.0183060

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